Cole cita a los cantantes Mary J. Blige y Brandy como sus mayores influencias e inspiraciones. Lanzó su primer álbum de platino The Way It Is en junio de 2007, y su otro álbum Just like
You en septiembre de 2007. Su tercer álbum, A Different Me salió a la venta el 16 de diciembre de 2008. La canción principal de ese álbum, "Playa Cardz Right", incluye al cantante de rap Tupac y fue oficialmente lanzado el 8 de octubre de 2008.
La tercera temporada de su reality de la BET, Keyshia Cole: The Way It Is comenzó el martes 11 de noviembre de 2008. Keyshia Cole (born October 15, 1981) is an American singer-songwriter.
She gained nationwide acclaim when her 2005 debut album, The Way It Is, was certified platinum by the RIAA. Her sophomore album, Just Like You, went into production shortly after and was released in September 2007 and certified platinum four months later. Her third studio album, A Different Me, was released in December 2008 and has been certified gold for shipping 900,000+ units in the United States.
All three of these albums were supported by her record breaking reality/documentary series Keyshia Cole: The Way It Is which aired on BET from 2006-2008, giving viewers a closer look into Cole's career and family life with her biological mother and sister.
After a two year hiatus, she released her fourth studio album, Calling All Hearts, in December 2010. Her fifth studio album, Woman to Woman is to be released in September 2012 being supported by her new reality show, Keyshia Cole: Family First.